Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia
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چکیده
منابع مشابه
Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia.
ETHNOPHARMACOLOGICAL RELEVANCE Corydalis dubia is used in Bhutanese traditional medicine as a febrifuge and for treating infections in the blood, liver and bile which correlate to the signs and symptoms of malarial and microbial infections. AIM OF THE STUDY To validate the ethnopharmacological uses of the plant and to discover potential new therapeutic drug leads. MATERIALS AND METHODS C. d...
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The chemical constituents and biological activities of Corydalis crispa (Fumariaceae) were investigated for the first time. The phytochemical study resulted in the isolation of nine known isoquinoline alkaloids: protopine (1), 13-oxoprotopine (2), 13-oxocryptopine (3), stylopine (4), coreximine (5), rheagenine (6), ochrobirine (7), sibiricine (8) and bicuculline (9), with complete NMR data for ...
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With the objective of determining safety and verifying the traditional uses of the Bhutanese medicinal plant, Pleurospermum amabile Craib & W. W. Smith, we investigated its crude extracts and the isolated phytochemicals for their biological activities. Four phenylpropanoids [(E)-isomyristicin (1), (E)-isoapiol (2), methyl eugenol (3) and (E)-isoelemicin (4)] and six furanocoumarins [psoralen (5...
متن کاملAntimalarial evaluation of selected medicinal plant extracts used in Iranian traditional medicine
Objective(s): In an attempt to discover new natural active extracts against malaria parasites, the present study evaluated the antiplasmodial properties of selected plants based on Iranian traditional medicine. Materials and Methods: Ten plant species found in Iran were selected and collected based on the available literature about the Iranian traditional medicine. The methanolic extracts of th...
متن کاملAntimalarial evaluation of selected medicinal plant extracts used in Iranian traditional medicine
OBJECTIVES In an attempt to discover new natural active extracts against malaria parasites, the present study evaluated the antiplasmodial properties of selected plants based on Iranian traditional medicine. MATERIALS AND METHODS Ten plant species found in Iran were selected and collected based on the available literature about the Iranian traditional medicine. The methanolic extracts of thes...
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ژورنال
عنوان ژورنال: Journal of Ethnopharmacology
سال: 2012
ISSN: 0378-8741
DOI: 10.1016/j.jep.2012.06.037